The crossword clue "Downer drug" was last seen in the Premier Sunday Crossword puzzle on June 16, 2024. We've carefully identified 67 possible answers from crossword puzzles published over the years. Among all candidates, OPIATE (6 letters) stands out as the strongest match at 99%, making it the most reliable solution for this particular clue.
Answer For Downer drug:
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67 Other Potential Answers
Rank
Answer
Length
Source
Date
99%
OPIATE
Downer drug
(6)
Premier Sunday Crossword
Jun 16, 2024
99%
OPIATE
Downer drug
Premier Sunday Crossword · Jun 16, 2024
99%
OPIOID
Downer drug
(6)
Premier Sunday Crossword
Dec 15, 2019
99%
OPIOID
Downer drug
Premier Sunday Crossword · Dec 15, 2019
8%
ITSSAD
"What a downer"
(6)
LA Times Daily Crossword
Sep 6, 2026
8%
ITSSAD
"What a downer"
LA Times Daily Crossword · Sep 6, 2026
8%
LSD
Trippy drug
(3)
LA Times Daily Crossword
Jul 31, 2026
8%
LSD
Trippy drug
LA Times Daily Crossword · Jul 31, 2026
8%
PREP
HIV prevention drug
(4)
Universal Crossword
Apr 5, 2026
8%
PREP
HIV prevention drug
Universal Crossword · Apr 5, 2026
8%
RITALIN
ADHD drug
(7)
Universal Crossword
Mar 17, 2026
8%
RITALIN
ADHD drug
Universal Crossword · Mar 17, 2026
8%
ACIDTAB
Dose of a trippy drug
(7)
Universal Crossword
Mar 12, 2026
8%
ACIDTAB
Dose of a trippy drug
Universal Crossword · Mar 12, 2026
8%
DOSED
Delivered a drug to
(5)
Universal Crossword
Jul 11, 2025
8%
DOSED
Delivered a drug to
Universal Crossword · Jul 11, 2025
8%
AZT
HIV-treating drug
(3)
Eugene Sheffer Crossword
Apr 17, 2025
8%
AZT
HIV-treating drug
Eugene Sheffer Crossword · Apr 17, 2025
8%
SENNA
Cathartic drug
(5)
Eugene Sheffer Crossword
Apr 9, 2025
8%
SENNA
Cathartic drug
Eugene Sheffer Crossword · Apr 9, 2025
8%
AMBIEN
Sleep aid drug
(6)
Eugene Sheffer Crossword
Mar 8, 2025
8%
AMBIEN
Sleep aid drug
Eugene Sheffer Crossword · Mar 8, 2025
8%
OPIUM
Poppy drug
(5)
Eugene Sheffer Crossword
Feb 28, 2025
8%
OPIUM
Poppy drug
Eugene Sheffer Crossword · Feb 28, 2025
8%
MEDICATE
Administer a drug to
(8)
Premier Sunday Crossword
Dec 22, 2024
8%
MEDICATE
Administer a drug to
Premier Sunday Crossword · Dec 22, 2024
8%
LDOPA
Parkinson's drug
(5)
Universal Crossword
Oct 7, 2024
8%
LDOPA
Parkinson's drug
Universal Crossword · Oct 7, 2024
8%
METH
“Breaking Bad” drug
(4)
Eugene Sheffer Crossword
Jul 13, 2024
8%
METH
“Breaking Bad” drug
Eugene Sheffer Crossword · Jul 13, 2024
8%
STATIN
Cholesterol drug
(6)
LA Times Daily Crossword
Jun 22, 2024
8%
STATIN
Cholesterol drug
LA Times Daily Crossword · Jun 22, 2024
8%
SOMA
"Brave New World" drug
(4)
LA Times Daily Crossword
May 10, 2024
8%
SOMA
"Brave New World" drug
LA Times Daily Crossword · May 10, 2024
8%
MICRODOSE
Very small amount of a drug
(9)
Eugene Sheffer Crossword
Apr 29, 2024
8%
MICRODOSE
Very small amount of a drug
Eugene Sheffer Crossword · Apr 29, 2024
8%
MARLO
"The Wire" drug lord Stanfield
(5)
LA Times Daily Crossword
Mar 12, 2024
8%
MARLO
"The Wire" drug lord Stanfield
LA Times Daily Crossword · Mar 12, 2024
8%
PHARMA
Big __: drug industry, colloquially
(6)
LA Times Daily Crossword
Mar 3, 2024
8%
PHARMA
Big __: drug industry, colloquially
LA Times Daily Crossword · Mar 3, 2024
8%
ABM
Rocket downer, for short
(3)
Premier Sunday Crossword
Feb 25, 2024
8%
ABM
Rocket downer, for short
Premier Sunday Crossword · Feb 25, 2024
8%
TRAFFICREPORT
Review that says, "Bit of a downer, but Soderbergh delivers"?
(13)
LA Times Daily Crossword
Dec 21, 2023
8%
TRAFFICREPORT
Review that says, "Bit of a downer, but Soderbergh delivers"?
LA Times Daily Crossword · Dec 21, 2023
8%
XANAX
Anti-anxiety drug
(5)
LA Times Daily Crossword
Nov 24, 2023
8%
XANAX
Anti-anxiety drug
LA Times Daily Crossword · Nov 24, 2023
8%
NARCO
Undercover drug cop
(5)
Universal Crossword
Sep 20, 2023
8%
NARCO
Undercover drug cop
Universal Crossword · Sep 20, 2023
8%
MED
Prescription drug, for short
(3)
Universal Crossword
Sep 19, 2023
8%
MED
Prescription drug, for short
Universal Crossword · Sep 19, 2023
8%
VALIUM
Anxiety drug brand
(6)
Universal Crossword
May 31, 2023
8%
VALIUM
Anxiety drug brand
Universal Crossword · May 31, 2023
8%
SURECURE
Miracle drug, maybe
(8)
Eugene Sheffer Crossword
Feb 1, 2023
8%
SURECURE
Miracle drug, maybe
Eugene Sheffer Crossword · Feb 1, 2023
8%
BETA
___ blocker (heart drug)
(4)
Universal Crossword
Nov 7, 2022
8%
BETA
___ blocker (heart drug)
Universal Crossword · Nov 7, 2022
8%
MORPHINE
Narcotic drug
(8)
Eugene Sheffer Crossword
Feb 10, 2022
8%
MORPHINE
Narcotic drug
Eugene Sheffer Crossword · Feb 10, 2022
8%
SEDATIVE
Calming drug
(8)
Eugene Sheffer Crossword
Jan 24, 2022
8%
SEDATIVE
Calming drug
Eugene Sheffer Crossword · Jan 24, 2022
8%
CHAPO
“El —” (nickname of a drug lord)
(5)
Premier Sunday Crossword
Jan 9, 2022
8%
CHAPO
“El —” (nickname of a drug lord)
Premier Sunday Crossword · Jan 9, 2022
8%
ZOCOR
Cholesterol-lowering drug
(5)
Premier Sunday Crossword
Jan 9, 2022
8%
ZOCOR
Cholesterol-lowering drug
Premier Sunday Crossword · Jan 9, 2022
8%
KKKKKKKKKUNIT
Team at a drug bust
(13)
LA Times Daily Crossword
Mar 11, 2021
8%
KKKKKKKKKUNIT
Team at a drug bust
LA Times Daily Crossword · Mar 11, 2021
8%
DILATOR
Pupil-widening drug, e.g.
(7)
Premier Sunday Crossword
Jan 17, 2021
8%
DILATOR
Pupil-widening drug, e.g.
Premier Sunday Crossword · Jan 17, 2021
8%
GUS
"Better Call Saul" drug lord Fring
(3)
LA Times Daily Crossword
Apr 23, 2020
8%
GUS
"Better Call Saul" drug lord Fring
LA Times Daily Crossword · Apr 23, 2020
8%
SIDEEFFECT
*Part of a long list in many drug commercials
(10)
Universal Crossword
Mar 5, 2020
8%
SIDEEFFECT
*Part of a long list in many drug commercials
Universal Crossword · Mar 5, 2020
8%
BRANDNAME
Nongeneric, as a drug
(9)
Eugene Sheffer Crossword
Dec 13, 2019
8%
BRANDNAME
Nongeneric, as a drug
Eugene Sheffer Crossword · Dec 13, 2019
8%
FBIRAID
Govt. drug bust, perhaps
(7)
LA Times Daily Crossword
Oct 1, 2019
8%
FBIRAID
Govt. drug bust, perhaps
LA Times Daily Crossword · Oct 1, 2019
8%
AARP
Group lobbying for lower drug prices
(4)
LA Times Daily Crossword
Sep 22, 2019
8%
AARP
Group lobbying for lower drug prices
LA Times Daily Crossword · Sep 22, 2019
8%
ALLEGRA
Pollen season drug brand
(7)
LA Times Daily Crossword
Apr 13, 2019
8%
ALLEGRA
Pollen season drug brand
LA Times Daily Crossword · Apr 13, 2019
8%
PARTD
Medicare prescription drug section
(5)
LA Times Daily Crossword
Dec 23, 2018
8%
PARTD
Medicare prescription drug section
LA Times Daily Crossword · Dec 23, 2018
8%
SULFA
Bacteria-fighting drug
(5)
LA Times Daily Crossword
Jun 23, 2018
8%
SULFA
Bacteria-fighting drug
LA Times Daily Crossword · Jun 23, 2018
8%
LIPITOR
Cholesterol-inhibiting drug
(7)
LA Times Daily Crossword
Jun 12, 2018
8%
LIPITOR
Cholesterol-inhibiting drug
LA Times Daily Crossword · Jun 12, 2018
8%
STASH
Hidden drug supply
(5)
LA Times Daily Crossword
Mar 13, 2018
8%
STASH
Hidden drug supply
LA Times Daily Crossword · Mar 13, 2018
8%
DOPA
L- — (drug treating Parkinson's)
(4)
Premier Sunday Crossword
Jan 28, 2018
8%
DOPA
L- — (drug treating Parkinson's)
Premier Sunday Crossword · Jan 28, 2018
1%
CVS
MinuteClinic drugstore chain
(3)
LA Times Daily Crossword
May 4, 2026
1%
CVS
MinuteClinic drugstore chain
LA Times Daily Crossword · May 4, 2026
1%
RANGE
Asset for Mariah Carey or a rural landowner
(5)
Universal Crossword
Mar 13, 2026
1%
RANGE
Asset for Mariah Carey or a rural landowner
Universal Crossword · Mar 13, 2026
1%
OTC
How some drugs are sold: Abbr.
(3)
Universal Crossword
Oct 2, 2025
1%
OTC
How some drugs are sold: Abbr.
Universal Crossword · Oct 2, 2025
1%
READE
Duane __: NYC drugstore chain
(5)
LA Times Daily Crossword
Jul 5, 2025
1%
READE
Duane __: NYC drugstore chain
LA Times Daily Crossword · Jul 5, 2025
1%
FDA
Org. that says no to some drugs
(3)
LA Times Daily Crossword
Apr 10, 2024
1%
FDA
Org. that says no to some drugs
LA Times Daily Crossword · Apr 10, 2024
1%
STATINS
Cholesterol-reducing drugs
(7)
Universal Crossword
Nov 16, 2023
1%
STATINS
Cholesterol-reducing drugs
Universal Crossword · Nov 16, 2023
1%
REEFER
"___ Madness" (classic anti-drug film)
(6)
Universal Crossword
Sep 27, 2023
1%
REEFER
"___ Madness" (classic anti-drug film)
Universal Crossword · Sep 27, 2023
1%
PSA
TV spot of Sonic telling you not to do drugs, e.g.
(3)
Universal Crossword
Oct 15, 2022
1%
PSA
TV spot of Sonic telling you not to do drugs, e.g.
Universal Crossword · Oct 15, 2022
1%
ELI
Lilly of drugs
(3)
Premier Sunday Crossword
Sep 18, 2022
1%
ELI
Lilly of drugs
Premier Sunday Crossword · Sep 18, 2022
1%
DRAM
Weight unit for a druggist
(4)
Premier Sunday Crossword
Jun 12, 2022
1%
DRAM
Weight unit for a druggist
Premier Sunday Crossword · Jun 12, 2022
1%
ORALLY
How some drugs are taken
(6)
Thomas Joseph Crossword
Jun 8, 2022
1%
ORALLY
How some drugs are taken
Thomas Joseph Crossword · Jun 8, 2022
1%
SULPHA
Class of antimicrobial drugs, in the British spelling
(6)
Premier Sunday Crossword
Feb 13, 2022
1%
SULPHA
Class of antimicrobial drugs, in the British spelling
Premier Sunday Crossword · Feb 13, 2022
1%
CLEAN
Off drugs
(5)
Universal Crossword
Sep 1, 2021
1%
CLEAN
Off drugs
Universal Crossword · Sep 1, 2021
1%
REEFERMADNESS
1936 anti-drug movie originally titled "Tell Your Children"
(13)
LA Times Daily Crossword
Nov 26, 2020
1%
REEFERMADNESS
1936 anti-drug movie originally titled "Tell Your Children"
LA Times Daily Crossword · Nov 26, 2020
1%
LAIRDS
Scottish landowners
(6)
Thomas Joseph Crossword
Oct 12, 2020
1%
LAIRDS
Scottish landowners
Thomas Joseph Crossword · Oct 12, 2020
1%
ONMEDS
Taking Rx drugs
(6)
Universal Crossword
Sep 18, 2020
1%
ONMEDS
Taking Rx drugs
Universal Crossword · Sep 18, 2020
1%
NOTO
“Just say — drugs”
(4)
Premier Sunday Crossword
Aug 16, 2020
1%
NOTO
“Just say — drugs”
Premier Sunday Crossword · Aug 16, 2020
1%
PEPPILLS
Uppers, drug-wise
(8)
LA Times Daily Crossword
Aug 11, 2020
1%
PEPPILLS
Uppers, drug-wise
LA Times Daily Crossword · Aug 11, 2020
1%
PSYCHOPHARMACOLOGICAL
Concerning the effects of drugs on the mind
(21)
Premier Sunday Crossword
Jan 6, 2019
1%
PSYCHOPHARMACOLOGICAL
Concerning the effects of drugs on the mind
Premier Sunday Crossword · Jan 6, 2019
1%
MEDS
Healing drugs, briefly
(4)
Premier Sunday Crossword
Aug 12, 2018
1%
MEDS
Healing drugs, briefly
Premier Sunday Crossword · Aug 12, 2018
1%
LAIRD
Scottish landowner
(5)
Thomas Joseph Crossword
Apr 7, 2018
1%
LAIRD
Scottish landowner
Thomas Joseph Crossword · Apr 7, 2018
1%
DEED
Landowner's document
(4)
LA Times Daily Crossword
Mar 5, 2018
1%
DEED
Landowner's document
LA Times Daily Crossword · Mar 5, 2018
Clues for Premier Sunday Crossword on June 16, 2024
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Frequently Asked Questions
How many possible solutions does "Downer drug" have?
We found 2 exact solutions and 67 total potential answers including similar clues. The most likely answer is OPIATE (6 letters).
What is the best answer for "Downer drug"?
The best answer for "Downer drug" is OPIATE with 6 letters.
This answer has a 99% confidence rating based on our database of crossword solutions.
Other exact solutions include OPIOID (6 letters).
Where has "Downer drug" been used as a crossword clue?
This clue has appeared 2 times in our database.
It has been featured in Premier Sunday Crossword.
It was last seen in the Premier Sunday Crossword on June 16, 2024.